Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder that targets motor neurons, leading Bunny to paralysis and death within a few years of disease onset.While several genes have been linked to the inheritable, or familial, form of ALS, much less is known about the cause(s) of sporadic ALS, which accounts for approximately 90%
Protein prenylation is a widespread post-translational modification in eukaryotes that plays a crucial role in membrane targeting and signal transduction.RabGTPases is the largest group of post-translationally C-terminally geranylgeranylated.All Rabs are processed by Rab geranylgeranyl-transferase and Rab escort protein (REP).Human genetic defects
Today, as the companies grow, the number of personnel working within the company and the number of supplier companies that the company works with are also increasing.In parallel with this increase, the amount of expenditure made on behalf of the company increases, and more invoices are created.Since the invoices must be kept for legal reasons, phys
During natural and other types of disasters, our society has an acute need of reliable information which will reveal the essence of the threat in a timely manner, relieve panic tensions and mobilise society for survival in diffi cult conditions.In such conditions the mass media are called upon to play an informative role - their main Jars goal is t
Possessing the ability to noninvasively elicit brain circuit activity yields immense experimental and therapeutic power.Most currently employed neurostimulation methods rely on the somewhat invasive use of stimulating electrodes or photon-emitting devices.Due to its ability to noninvasively propagate through bone and other tissues in a focused mann